| CASE REPORT |
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| Year : 2015 | Volume
: 57
| Issue : 3 | Page : 311-312 |
Prolonged, longstanding, ultra-high-dose abuse of sildenafil
TS Sathyanarayana Rao1, V Arun Kumar1, Rajesh Raman1, Chittaranjan Andrade2
1 Department of Psychiatry, JSS Medical College and Hospital, JSS University, Mysore, Karnataka, India
2 Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India
Correspondence Address:
T S Sathyanarayana Rao
Department of Psychiatry, JSS Medical College and Hospital, JSS University, Mysore - 570 004, Karnataka
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0019-5545.166626
We report a 40-year-old male who self-administered sildenafil for 10 years, in progressively increasing doses from 100 mg per occasion in the 1 st year to 1300 mg per occasion in the 9 th – 10 th years of (ab)use. The frequency of abuse was 2 – 3/week. The only adverse effect of concern that was reported was transient (up to about 12 h), self-limited blurring of vision in the last 2 years, especially in the last 2 months at the highest dose. The patient was otherwise normal. This report is unique because it describes what may be the highest dose of sildenafil reported in literature, abused across a protracted period of time. We discuss issues related to dose and safety of and tolerance to the drug.
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