Indian Journal of PsychiatryIndian Journal of Psychiatry
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Year : 2014  |  Volume : 56  |  Issue : 3  |  Page : 295-297

Acute psychosis induced by isotretinoin

Girishwari Hospital, Chennai, Tamil Nadu, India

Correspondence Address:
Dr. Sundararajan Rajagopal
Girishwari Hospital, 19 K.B. Dasan Road, Chennai - 600 018, Tamil Nadu
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0019-5545.140652

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Isotretinoin is used for the treatment of severe acne. Psychiatric side-effects, particularly depression, have been well-documented. This dramatic case report is about a young male patient who developed acute psychosis within a few days of starting isotretinoin. Due to his persecutory delusions, the patient, who was an Indian engineer working in Germany, decided to immediately return to India fearing for his life in Germany. Careful history taking established the cause of the psychosis. Isotretinoin was stopped; patient showed rapid improvement, within a week, on a low dose of risperidone. Risperidone was continued as a precaution for 3 months. After a further 8 months, the patient remains well without any psychotropic medication.



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