Indian Journal of PsychiatryIndian Journal of Psychiatry
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Year : 2006  |  Volume : 48  |  Issue : 4  |  Page : 254-257

The course of bipolar disorder in rural India

1 Department of Psychiatry, National Institute of Mental Health and Neuro Sciences (NIMHANS), Hosur Road, Bangalore 560029, Karnataka, India
2 Department of Bio-Statistics, National Institute of Mental Health and Neuro Sciences (NIMHANS), Hosur Road, Bangalore 560029, Karnataka, India

Correspondence Address:
Mohit P Chopra
Assistant Professor in Psychiatry, 4301 W. Markham Street, # 825, Little Rock, AR 72205
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0019-5545.31559

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Aim: To examine the naturalistic course of bipolar disorder in a rural, community-based, partially treated cohort. Methods: All patients diagnosed with bipolar disorder during an epidemiological survey (n=34) in a rural area in India were followed longitudinally using standardized instruments, and the life-chart method used to examine their course. Results: Seven (26%) of the 27 patients evaluated directly had not received any treatment whatsoever. Four patients (15%) had experienced rapid-cycling at some time; patients without rapid-cycling had experienced a mean 0.22 episodes/year. Episodes of mania accounted for 72% of all episodes. None of the variables examined appeared to predict the total number of episodes experienced by individual patients, although rapid-cycling occurred significantly more often if the patients had not received any psychopharmacological treatment. Conclusions: A mania-predominant course was observed in this small cohort, similar to reports from other developing countries.



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