Indian Journal of PsychiatryIndian Journal of Psychiatry
Home | About us | Current Issue | Archives | Ahead of Print | Submission | Instructions | Subscribe | Advertise | Contact | Login 
    Users online: 1737 Small font sizeDefault font sizeIncrease font size Print this article Email this article Bookmark this page
Search Again
 Table of Contents
 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Article Access Statistics
 Reader Comments
 Email Alert
 Add to My List
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded299    
    Comments [Add]    
    Cited by others 1    

Recommend this journal

Year : 2005  |  Volume : 47  |  Issue : 1  |  Page : 33-38

Substance abuse co-morbidity in schizophrenia: An inpatient study of course and outcome

1 Universal College of Medical Sciences, PB-53, Ranigaon, Bhairahawa, Nepal
2 Central Institute of Psychiatry, Kanke, Ranchi 834006, Jharkhand, India
3 'Chetna'-Institute for the Mentally Retarded, Regional Training Centre, Sector-C, Aliganj, Lucknow 226024, Uttar Pradesh, India

Correspondence Address:
Tapas K Aich
52, Betiahata (South), Near Premchand Park, Gorakhpur, Uttar Pradesh
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0019-5545.46072

Rights and Permissions

Background: Differences in opinion exist among researchers in relation to the course and outcome of substance abuse co-morbidity in schizophrenia. Aim: To compare the pattern of remission of symptoms in positive and negative schizophrenics with and without a history of substance abuse. Methods: Seventy schizophrenics were divided into two groups based on the history of presence or absence of substance abuse/dependence. Thirty-eight patients (54.3%) were diagnosed as having co-morbid alcohol/ substance abuse/dependence. Patients were rated at two-weekly intervals on the Positive and Negative Syndrome Scale (PANSS) with one follow-up rating by the end of the third month. Co-morbid substance abusers were predominantly represented by a positive syndrome and non-abusers by a negative syndrome at the time of admission. Results: Psychopathology remitted much faster in the substance-abusing group but after discharge, these patients tend to return to their pre-admission state. Conclusion: The following hypothesis is proposed based on the findings of the present study: 'Short-term inpatient outcome of substance-abusing schizophrenics is significantly better than non-substance abusing schizophrenics because of the faster rate of remission of their symptoms.' A corollary to the above hypothesis may be evolved-'through intense inpatient follow-up one may be able to differentiate substance-abusing and non-abusing schizophrenics'.



Print this article         Email this article