Indian Journal of PsychiatryIndian Journal of Psychiatry
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Year : 2002  |  Volume : 44  |  Issue : 3  |  Page : 240-245

A Clinical Genetic Study of Adult Obsessive Compulsive Disorder from India

1 Consultant Psychiatrist, St. Jude's Hospital, V /Foil, St Lucia, P.O. Box 331, West Indies, Saint Lucia
2 Senior Resident, Department of Psychiatry, Post Graduate Institute of Medical Education and Research, Chandigarh, India
3 Additional Professor, Department of Psychiatry, National Institute of Mental Health and Neuro Sciences, Bangalore, India

Correspondence Address:
R Guruswamy
Consultant Psychiatrist, St. Jude's Hospital, V /Foil, St Lucia, P.O. Box 331, West Indies
Saint Lucia
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Source of Support: None, Conflict of Interest: None

PMID: 21206578

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Objective: The current study aims to replicate western reports of a familial excess of syndromal and sub-syndromal Obsessive Compulsive Disorder (OCD) in OCD probands in an Indian population. Method: 148 relatives of OCD probands were compared with 151 normal subjects, based on evaluation on Schedule for Clinical Assessment for Neuropsychiatry (SCAN). Results: There were no clinically significant differences in the prevalence of psychiatric disorders between the two samples. Conclusion: In an Indian setting, the absence of familial loading in adult OCD is being reported. Whether subgroups of OCD are familial, or other factors play a role in the pathogenesis of OCD in India needs to be explored.



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