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| Year : 1998 | Volume
: 40
| Issue : 1 | Page : 70-72 |
Clozapine-induced Agranulocytosis and Use of G-CSF
TN Srinivasan1, Kuruvilla Thomas2
1 Research Consultant, Schizophrenia Research Foundation (India), Plot R/7A, West Main Road, Chennai-600101, India
2 Consultant Paediatrician, Sundaram Medical Foundation, 4th Avenue, Shanthi Colony, Anna nagar (West), Chennai - 600 040, India
Correspondence Address:
T N Srinivasan
Research Consultant, Schizophrenia Research Foundation (India), Plot R/7A, West Main Road, Chennai-600101
India
 Source of Support: None, Conflict of Interest: None  | Check |
PMID: 21494447 
Use of clozapine is attended with the serious though rare risk of agranulocytosis. Clozapineinduced agranulocytosis is reversible with the use of cytokines like granulocyte-colony stimulating factor (G-CSF). Reports of the haematological complication of clozapine have not been forthcoming from India though it has been in use for nearly three years. This report is on an young patient who developed total absence of granulocytes during the 4th month of treatment who was successfully treated with G-CSF.
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